Percutaneous Nonviral Delivery of Hepatocyte Growth Factor in a Fracture Gap Promotes Bone Repair in Rabbits: A Preliminary Study Running title: HGF on Fracture Healing

Potential Role of Local Estrogen in Enhancement of Fracture Healing: Preclinical Study in Rabbits

      Background: Effects of estrogen on bone metabolism and its protective role on prevention of osteoporosis are well   documented. However, the efficacy of estrogen treatment on bone healing is not well investigated. The drug can be delivered both systemically or locally to the bone with differences in concentrations and side effects. The aim of this study was to investigate the effect of lo...

Effect of semisynthetic extracellular matrix-like hydrogel containing hepatocyte growth factor on repair of femoral neck defect in rabbits.

Using tissue engineering technology research to develop organized artificial bone, then repair bone defect. This work aims to investigate the role of semisynthetic extracellular matrix-like hydrogel (sECMH) containing hepatocyte growth factor (HGF) on repair of femoral neck defect in rabbits. 18 New Zealand rabbits were used in this study. According to autologous paired comparison method, the l...

Percutaneous Bone Marrow Grafting in Radial Fracture in Rabbits

اثر امواج فراصوتی کم توان بر رشد استخوان در داخل کانال ایمپلانت تیتانیومی

The effect of ultrasound waves with low intensity on reducing the time of repair and healing of bone fracture has been known. The present research was undertaken to investigate the effect of ultrasound waves on acceleration of bone growth and, finally, on repair and healing of surgical area using in-vivo animal experiment. In this study, 20 titanium implants with proper dimensions wer...

Elastic cartilage grafting in canine radial fracture

Bone has a capability to repair itself when it is fractured. Repair involves the generation of intermediatetissues, such as fibrous connective tissue, cartilage and woven bone, before final bone healing can occur. Theprocess of cartilage-to-bone transition (CBT) is a key for the achievement of rigid bone healing duringfracture repair. We tested this potential for elastic cartilage using a long ...